Consider the search volume for your chosen topic. Find out how many people are searching for that topic by running a web search for, say, "quick weight loss." The quotes will make your search specific, so that the only results will be sites that mention the exact phrase "quick weight loss." Your search engine should list the number of search results that turn up for your query. Try to find a topic that turns up fewer than 5,000 results.
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Always disclose your affiliate relationship. Most visitors will probably understand that graphic ads will lead to your getting paid, but if you write a review or use an in-text link as a recommendation, you want your readers to know that may lead to compensation as well. This ensures you retain transparency and trust with your readers, but also, it's required by the FTC's endorsement rules.